Muse Cell Basics

Discovered by Dr. Mari Dezawa in 2010, these naturally occurring pluripotent stem cells are found in various tissues, including bone marrow and umbilical cord blood. Their unique properties, such as stress resistance and the ability to spontaneously differentiate into multiple tissue types, make them a promising option for innovative therapies. Join us in the future of regenerative medicine and the healing possibilities that Muse offers. You do NOT have to be a Kardashian to be able to afford this treatment. We are here to offer you options and help educate you to see if Muse Cell is truly the best option for your health issues. We are proud & honored to offer our patients access to this treatment.

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The Discovery of Muse Cells

MUSE Cells were discovered by Professor Mari Dezawa and her team at Tohoku University in Japan in 2010. The discovery arose during research into adult stem cells and their potential for regenerative medicine. Professor Dezawa and her colleagues identified a specific subpopulation of stem cells that exhibited unique qualities like stress resistance and multilineage-differentiation, distinguishing them from other stem cells.

The breakthrough came when researchers observed that certain adult mesenchymal stem cells could survive in extreme environments, such as in the presence of Reactive Oxygen Species (ROS) or under serum deprivation, where most other cells would perish. These cells also expressed key Pluripotent surface markers like SSEA-3, which is typically associated with embryonic stem cells. This combination of resilience and pluripotency led to their identification as MUSE Cells.

Muse Cell Benefits

1. Pluripotency Without Tumor Risk

Muse cells can differentiate into cell types from all three germ layers: ectoderm, mesoderm, and endoderm.
Unlike embryonic stem cells or induced pluripotent stem cells (iPSCs), Muse cells do not form tumors.

2. Natural Homing Ability

When injected into the bloodstream, Muse cells migrate directly to damaged tissues, guided by biological signals like sphingosine-1-phosphate (S1P).
This targeted approach enhances their effectiveness in tissue repair.

3. Stress Resistance

Muse cells survive in harsh environments, such as low oxygen or high inflammation, making them ideal for treating injuries and chronic conditions

4. Broad Therapeutic Applications

Muse cells are being studied for a wide range of conditions, including:

🧠 Neurological disorders: Parkinson’s, ALS, stroke recovery
❤️ Cardiovascular issues: heart attack repair
🦴 Musculoskeletal injuries: spinal cord damage, muscle regeneration
🛡️ Autoimmune diseases: potential modulation of immune response

5. Immune Privilege

Muse cells exhibit a unique immune privilege system, meaning they can evade detection and rejection by the host’s immune system—even when sourced from another individual or species2.
This allows them to survive long-term in host tissues without immunosuppressive drugs or HLA matching, which is a major advantage in clinical applications

6. Tissue Repair and Immune Balance

By differentiating into tissue-compatible cells at the site of injury, Muse cells replace damaged or apoptotic cells, which helps restore tissue integrity and reduce chronic inflammation.
Their presence promotes a trophic effect, supporting surrounding cells and contributing to immune homeostasis